Correction to: Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons
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چکیده
منابع مشابه
Hippocampal neurons of mice deficient in DNA-dependent protein kinase exhibit increased vulnerability to DNA damage, oxidative stress and excitotoxicity.
DNA damage has been documented in neurodegenerative conditions ranging from Alzheimer's disease to stroke. DNA-dependent protein kinase (DNA-PK) is involved in V(D)J recombination and DNA double strand break repair, and may play a role in cell death induced by DNA damage. We now report that cultured hippocampal neurons from severe combined immunodeficient (scid) mice which lack DNA-PK activity ...
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ژورنال
عنوان ژورنال: Molecular Neurobiology
سال: 2020
ISSN: 0893-7648,1559-1182
DOI: 10.1007/s12035-020-01890-w